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98% Phloretin Powder

Specifications: 98%

Detection method: HPLC

Source: apple peel, root bark


Molecular formula: C15H14O5

Molecular weight: 274.27


Shipping speed:1-3 days

Inventory:In stock

Certificates:HACCP, HALAL, KOSHER, ISO9001, ISO22000, FDA

    What is phloretin?

    Phloretin, also known as trihydroxyphenolacetone, is a flavonoid compound. It is a natural active substance found in the juices of apples, pears and other fruits and various vegetables. It can protect plants from ultraviolet damage. Phloretin has a wide distribution range and is named after it is found in the root bark of apple and other fruit trees. It has been more than 100 years since the discovery and separation. Phloretin has antioxidant, anti-inflammatory, transdermal absorption, whitening, and moisturizing effects. Phloretin can be used in facial masks, skin care creams, lotions and essences. It is a pearl white crystalline powder, soluble in ethanol and acetone, and almost insoluble in water.
    Phloretin is a new natural skin whitening agent commonly used in facial masks, creams, lotions and essences. It can inhibit the excessive secretion of sebaceous glands and is used to treat excessive secretion of acne. It can inhibit the activity of melanocytes and has an effect on various skin spots. Compared with similar natural ingredients arbutin and kojic acid, phloretin at the same concentration has better inhibitory effect on tyrosinase than them, and when compounded with arbutin or kojic acid, it can greatly improve the inhibitory effect on tyrosinase. Tyrosinase inhibition rate, thereby achieving whitening effect. Phloretin has a particularly strong moisturizing effect and can absorb 4-5 times its own weight in water. It can promote the absorption of other functional factors in the formula so that it can exert better effects. It also has strong antioxidant capacity and can remove the contents of the skin. free radicals.

    What are the benefits

    1. Antioxidant, anti free radical
    Phloretin has strong antioxidant properties, has an antioxidant effect on oil, and can scavenge free radicals in the skin.

    2. Whitening spots
    The whitening mechanism of phloretin is mainly to inhibit the activity of tyrosinase in the body, thereby reducing the production of melanin in the body.

    3. Promote transdermal absorption
    Phloretin is a lipophilic compound that penetrates into the skin via intercellular lipids

    4. Anti-inflammatory activity
    In the anti-inflammatory experiment of phloretin, in vitro studies have shown that phloretin can inhibit the production of inflammatory factors, chemokines and differentiation factors

    5. Sunscreen
    Phloretin has a certain ability to absorb ultraviolet rays. Adding phloretin to the basic formula of cosmetics can improve the SPF and SPA values of cosmetics.

    6. Antibacterial activity
    Phloretin is a flavonoid compound with bacteriostatic activity

    7. Moisturizing effect
    The 4 hydroxyl groups contained in the phloretin molecule can form hydrogen bonds with water molecules to absorb water and have a potential moisturizing effect. Therefore, phloretin can also be used as a natural moisturizer in moisturizing cosmetics.

    8. Anti-hair loss effect
    Studies have shown that phloretin can inhibit the activity of soybean lipoxygenase, thereby reducing hair loss due to premature aging, indicating that phloretin has a potential anti-hair loss effect, and can be used as an anti-hair loss raw material to be added to shampoo and hair care. in the element.

    Product Usage & Recommended Dosage

    Specification Recommended dose
    Phloretin 98% 0.3%-2.0%
    Phloretin is widely used in masks, lotions, essences, creams, sunscreens, shampoos, conditioners and other types of cosmetics and care products.
    98% Phloretin Powderqeu

    Research on phloretin and cosmetics

    Pilot projects


    Effect description

    Elimination of free radical DPPH


    Elimination rate: 74.6%

    Inhibition of lipid peroxidation


    Inhibition rate: 53%

    Promotion of type 4 collagen production by phloretin in cell culture


    Promotion rate: 201.6±20.6 (blank 100)

    The protection of phloretin on apoptosis of stratum corneum cells under 1.0J/cm2 UVB irradiation


    Protection rate: 51.3%v9.6%

    The promotion of brain amide production by phloretin in cell culture


    Promotion rate: 164 (blank 100)

    Inhibition of tyrosinase activity


    Inhibition rate: 82.2%

    Inhibition of hyaluronidase activity


    Inhibition rate: 93.5%

    Inhibition of 5α-reductase activity

    Half inhibitory dose IC50: 84.3ug/mL

    Inhibition of metalloprotease MMP-1 activity


    Inhibition rate: 78%

    Inhibition of interleukin IL-4 production

    Half inhibitory dose IC50: >30umol/L

    Inhibition of β-hexosaminidase activity


    Inhibition rate: 93.5%

    Inhibition of transepidermal water evaporation by coating phloretin


    Inhibition rate: 25% (compared with blank)


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