What is Salicin from White Willow Bark Extract?
2025-01-02
What is Salicin from White Willow Bark Extract?
White Willow Bark Extract is a natural product mainly derived from the bark of the white willow tree. It contains a variety of active ingredients, of which salicin is one of its main active ingredients. White Willow Bark Extract has a variety of pharmacological effects, including dispelling wind and dampness, reducing swelling and pain, and reducing fever.
Salicin is an alcohol-β-glycoside containing D-glucose. It is an anti-inflammatory agent produced by willow bark. As a natural, non-selective inhibitor of COX1 and COX2, salicin has antipyretic, analgesic and anti-rheumatic effects.
Salicin, an anti-inflammatory ingredient, is also known as willow bark extract (Willowbark). It is a colorless crystal or white powder with hygroscopicity. It is widely present in the bark and leaves of various willow and poplar plants. For example, purple willow bark contains up to 25% salicin.
Salicin is a phenol β-glucoside obtained from willow bark and has anti-inflammatory effects. Salicin is a prodrug that is gradually transported to the lower part of the intestine, hydrolyzed by intestinal bacteria into salicyl alcohol, and converted into salicylic acid after absorption. Therefore, it produces an antipyretic effect without causing stomach damage.
The main component of white willow bark extract is salicin, which is an effective anti-inflammatory ingredient traditionally used to heal wounds and relieve muscle pain. In addition, salicin also has skin care effects such as anti-wrinkle, anti-aging, anti-inflammatory and anti-acne. It can affect the regulation of genes in the skin and regulate gene groups related to the biological process of skin aging, thereby achieving anti-wrinkle effects. Salicin plays an important role in the production and maintenance of collagen in the skin, so it can increase skin elasticity and achieve anti-wrinkle effects. White willow bark extract has a significant life-extending effect on yeast, up to 5 times, and is a highly potential anti-aging ingredient.
What are the effects of salicin from white willow bark extract?
1. Anti-wrinkle and anti-aging
Salicin can affect the regulation of genes in the skin, especially those gene groups related to the biological process of skin aging, which are called functional "young gene groups". In addition, salicin plays an important role in the production and maintenance of collagen, one of the key proteins in the skin, so it can increase skin elasticity and achieve anti-wrinkle effects.
2. Anti-inflammatory and anti-acne
Salicin has aspirin-like properties and has certain anti-inflammatory effects. It can be used to relieve facial acne, herpetic inflammation and sunburn. It contains salicylic acid, a BHA, which is a natural exfoliant used in several acne treatments because it helps the skin shed dead cells while clearing pores.
3. Exfoliation
Salicin contains salicylic acid, a natural exfoliant that helps the skin shed dead cells while clearing pores, reducing abnormal shedding of hair follicle walls and preventing acne.
4. Antipyretic and analgesic
Salicin has antipyretic and analgesic effects, which makes it used in medicine to treat fever and pain symptoms. For example, fever caused by colds or infections can be treated with salicin. In addition, it can relieve joint pain and back pain.
What is the anti-inflammatory mechanism of salicin?
Salicin belongs to the class of phenolic glycosides and is widely found in the bark and leaves of plants of the genera Willow and Populus. As an organic substance, salicin has a variety of biological activities and uses. Its application in the fields of medicine and cosmetics is mainly due to its anti-inflammatory, antipyretic and analgesic effects.
The anti-inflammatory effect of salicin is mainly related to its chemical structure and pharmacological properties. It has properties similar to aspirin and can exert its anti-wrinkle effects, increase skin gloss and elasticity, reduce pigmentation, and increase skin moisture by inhibiting the activity of NADH oxidase.
Does salicin from white willow bark extract really have anti-aging effects?
Salicin from white willow bark extract does have a certain anti-aging effect. Salicin, the main active ingredient in white willow bark extract, not only affects the regulation of genes in the skin, but also regulates gene clusters related to the biological process of skin aging, which are called functional young gene clusters. This means that salicin can slow down the process of skin aging by regulating the gene expression of skin cells.
Salicin plays an important role in the production and maintenance of collagen, one of the key proteins in the skin, which can increase skin elasticity and achieve anti-wrinkle effects.
Some experiments have shown that the anti-aging effect of white willow bark extract is real. For example, one trial found that white willow bark extract containing salicin can effectively improve the pain relief ability of arthritis patients after taking it for two consecutive months. Another trial found that after taking a certain amount of white willow bark extract every day, it can have a better effect on treating joint pain and/or arthritis within two weeks. This suggests that white willow bark extract may achieve anti-aging effects by inhibiting inflammatory responses.
What can salicin be used for?
Cosmetic field
Salicin is used as an anti-aging ingredient in cosmetics to increase the skin's radiance and elasticity. It also has high anti-inflammatory activity and can be used to treat facial acne, herpetic inflammation and sunburn.
Salicin is a natural exfoliant (BHA) that can be used in acne treatment to help the skin shed dead cells and clear pores.
Food field
Salicin has a powerful antibacterial component and can be added to food care formulations as a natural preservative to help extend the shelf life of the finished product.
Medical field
Salicin is an effective anti-inflammatory ingredient that has been traditionally used to relieve muscle pain and heal wounds. It can also be used to treat mild fever, colds, infections (flu), acute and chronic rheumatic discomfort, headaches and pain caused by inflammation.
Salicin is believed to have anti-inflammatory and analgesic abilities and can be used to treat arthritis and low back pain. Experiments have shown that products containing salicin have a good effect on relieving pain in patients with arthritis.
Salicin has skin care effects of anti-wrinkle, anti-aging, anti-inflammatory and anti-acne. It can affect the regulation of genes in the skin and maintain collagen production, thereby increasing skin elasticity.