01
66-84-2 Glucosamine hydrochloride Glucosamine hcl powder
What is glucosamine hydrochloride?
D-glucosamine hydrochloride (also known as glucosamine hydrochloride) is a drug for the treatment of bone and joint diseases and an antibiotic synergist. It is also a sweetener and antioxidant in food, and can also be used as a nutritional supplement for diabetic patients. Glucosamine hydrochloride and its derivatives have broad application prospects in the fields of medicine, light industrial cosmetics and other fields.
Glucosamine hydrochloride is one of the important drugs used clinically to treat osteoarthritis. Glucosamine hydrochloride stimulates the biochemical synthesis of mucopolysaccharides and increases the uptake of bone calcium, improves the metabolic function and nutrition of bones and soft tissues, increases the synthesis of synovial fluid, and provides joint lubrication. It can also block the pathological process of osteoarthritis and prevent the progression of the disease. Improve joint mobility, relieve pain and reduce joint deformation.
Pharmacological effects
Glucosamine is an amino monosaccharide that exists in the body, especially in articular cartilage. It is an important component necessary for the synthesis of proteoglycans in the matrix of human articular cartilage. It selectively acts on bony joints and blocks the pathology of bony joints. process, stimulates chondrocytes to produce glycoproteins with a normal polymer structure, and can also inhibit the activity of enzymes that damage cartilage, such as collagen and phospholipase A2, and inhibit the production of superoxide free radicals that damage cells, preventing corticosteroids and Certain NSAIDs damage chondrocytes and reduce the release of endotoxin factors that damage the cells. Through the above-mentioned pathways, this product has a direct anti-inflammatory effect, which can relieve pain symptoms of bone and joints, improve joint function, and prevent the development of osteoarthritis.
Glucosamine specifically targets cartilage, supplements cartilage nutrition, accelerates its regeneration and repair, and thus relieves pain caused by arthritis.
Glucosamine will increase mucopolysaccharides, including the repair of bone joint surfaces, especially osteoarthritis, or joint cavity lubricants are very helpful. Therefore, for elderly people with joint degeneration or elderly osteoarthritis, glucosamine is often needed to improve cartilage function or joint cavity function. However, glucosamine hydrochloride is relatively safe and will not cause other problems.
Glucosamine hydrochloride not only removes harmful metabolic substances from the joints, but also replenishes the joints with lubricating fluid. Cartilage that is malnourished, thin and brittle due to insufficient lubrication will return to health. Of course, calcium supplementation is also essential. It will increase bone density and make the bones of middle-aged and elderly people stronger.
Application direction
Glucosamine hydrochloride can be made into drugs to treat rheumatoid arthritis, ulcers, and enteritis. It is a nutritional additive for food and cosmetics, and a culture agent for biochemical cells.
Test Report
Analyze content | Quality Standard | Analyze results |
Exterior | white crystal | conform |
content | 99.0~101.0 % | 99..3 % |
Specific rotation | +70.0-+73.00 | +72.70 |
Transmittance | >90.0 % | 97.1 % |
Absorbance | <0.25n.u. | 0.16a.u. |
Loss on drying | ≤1.0 % | 0.04 % |
Burning residue | ≤0.1 % | 0.01 % |
pH value | 3.5-5.0 | 4.2 |
chloride | 16.2 %-16.7 % | 16.5 % |
Sulfate | ≤0.24 % | 0.19 % |
granularity | ≥30mesh | ≥30mesh |
Bulk density | ≥0.75g/ml | 0.77g/ml |
heavy metal | ≤10ppm | <10ppm |
arsenic | ≤0.5ppm | <0.5ppm |
total number of microorganisms | MAX1000/g | MAX100/g |
Yeast, mold | MAX100/g | MAX30/g |
E. coli | Not allowed to be detected | not detected |
salmonella | Not allowed to be detected | not detected |