Is Deoxyarbutin safe for skin?

What Is DeoxyArbutin?

Arbutin has three "brothers": β-arbutin, α-arbutin and deoxyarbutin (D-Arbutin).

Deoxyarbutin is a new generation of cosmetic skin lightening and whitening active agent, mainly used in advanced whitening cosmetics. It can effectively inhibit tyrosinase activity, regulate the production of melanin, overcome pigmentation, and lighten black spots on the skin. It has a rapid and lasting skin whitening effect. Deoxyarbutin also has a strong antioxidant effect. The inhibitory effect of deoxyarbutin on tyrosinase is significantly better than other whitening active agents. The whitening effect is 350 times that of arbutin, 150 times that of kojic acid, 10 times that of hydroquinone, 350 times that of β-arbutin, and 38.5 times that of α-arbutin. Its whitening effect can be maintained for 8 weeks after stopping use. More experiments have shown that while maintaining 95% cell survival, the toxicity of deoxyarbutin is still much lower than that of hydroquinone. Deoxyarbutin is not only non-toxic and non-irritating to the skin, but also easily absorbed by the skin. A small amount of use can show a whitening and skin lightening effect. It is considered to be a very safe cosmetic whitening active agent.

What Are The Functions Of DeoxyArbutin?

The human stratum corneum is more conducive to the absorption of fat-soluble ingredients. Deoxyarbutin removes all the sugars on the sugar side chain in its structure, increases the hydrophobicity of the molecule, and exhibits higher inhibition of tyrosinase activity, so the whitening effect is better.

As a competitive tyrosinase inhibitor, deoxyarbutin can regulate the production of melanin, overcome pigmentation, and lighten dark spots on the skin, with a rapid and lasting skin whitening effect.

What Is The Application Of DeoxyArbutin?

‌Deoxyarbutin is mainly used in advanced whitening cosmetics. ‌

As a new generation of cosmetic skin lightening and whitening active agent, deoxyarbutin has a rapid and lasting skin whitening effect. Its main application areas include:

‌1. Cosmetics‌: Deoxyarbutin is used as a cosmetic ingredient in advanced whitening cosmetics, such as creams, essences, etc., to help lighten dark spots on the skin and reduce pigmentation, thereby achieving the effect of whitening and brightening the skin.

‌2. Skin care‌: Due to its strong antioxidant effect, deoxyarbutin is also considered to be a very safe compound with a reversible skin lightening effect. It is suitable for all skin types and helps improve uneven skin tone and dullness.

The recommended amount of deoxyarbutin added in cosmetics is 0.1%-3%, in order to ensure its whitening effect while taking into account the skin's tolerance and safety. In addition, deoxyarbutin has low cytotoxicity and is considered to be a safe and effective whitening ingredient, which is widely used in various advanced whitening products‌.