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What is the use of Kojic acid dipalmitate?

2024-08-29

What Is Kojic Acid Dipalmitate?

Kojic acid dipalmitate is a chemical substance, also known as a kojic acid derivative. It is a white powder or needle-shaped crystal, mainly used as a whitening additive in cosmetics. Kojic acid dipalmitate is a fat-soluble derivative of kojic acid. It overcomes the shortcomings of kojic acid's instability to light and heat and discoloration when encountering metal ions, and has excellent compounding properties. It is not only easily absorbed by the skin, but also can bring good moisturizing effect to the skin. In cosmetics, the amount of kojic acid dipalmitate used is usually 1~3% of the total amount, and it has been recognized by the medical community and the Ministry of Health for lightening facial spots. It is a whitening ingredient with both whitening effect, safety and texture.

What Is The Mechanism Of Action Of Kojic Acid Dipalmitate?

Kojic acid dipalmitate has a strong inhibitory effect on the production of melanin in human skin. In terms of inhibiting the activity of tyrosinase, kojic acid dipalmitate is different from arbutin, isoflavone compounds, placental extract and Ascorbic Acid. Its unique feature is that it combines with copper ions during action, preventing the activation of copper ions and tyrosinase. It can also inhibit the production of melatonin pigments, black spots and freckles, promote skin metabolism, quickly eliminate the melatonin pigments that have been formed, and achieve whitening results in a short period of time.

What Are The Functions Of Kojic Acid Dipalmitate?

Kojic acid dipalmitate is a new generation of whitening additives after arbutin and kojic acid. It can improve the volatility of kojic acid, effectively inhibit the activity of tyrosinase, and block or delay the formation of melanin. Kojic acid dipalmitate has high stability that vitamin C does not have, no side effects, antioxidant effect, can quickly penetrate the skin, be absorbed by the skin, and soften the stratum corneum.

What Is The Application Of Kojic Acid Dipalmitate?

Kojic acid dipalmitate is mainly used in the field of cosmetics, especially as a whitening additive. ‌

Kojic acid dipalmitate is a new type of whitening ingredient. In addition, it also has an antioxidant effect, can quickly penetrate the skin, be absorbed by the skin, soften the stratum corneum, and has an excellent repair effect on skin problems such as chloasma, age spots, and pigmentation. Due to its high stability and no side effects, kojic acid dipalmitate is not only recognized by the medical community, but also widely used in cosmetics to fade facial spots, provide whitening effects, safety and texture. ‌

Kojic acid dipalmitate can be added to creams and lotions to make therapeutic cosmetics and whitening cosmetics that are effective for age spots, freckles and pigmentation. It is soluble in hot liquid paraffin, isopropyl palmitate, isopropyl myristate and other oils, which makes it easy to add it to the oil phase of cosmetics, and the amount is usually 1~3% of the total amount.

Difference between Kojic Acid Dipalmitate and Kojic Acid

The main differences between Kojic Acid Dipalmitate and Kojic Acid are their chemical structure, usage and effects. ‌

1.Chemical structure‌: Kojic Acid Dipalmitate is a fat-soluble derivative of Kojic Acid. Kojic Acid is combined with Palmitic Acid through esterification reaction to form white powder or needle-shaped crystals. This structural change not only makes Kojic Acid Dipalmitate overcome the shortcomings of Kojic Acid's instability to light and heat and discoloration when encountering metal ions, but also because there is no hydroxyl group in its molecular structure, it will not form hydrogen bonds with preservatives, sunscreens or other active ingredients in the cosmetic system, thereby affecting the efficacy of these additives, and has excellent compounding properties‌.

2.Usage: Kojic acid dipalmitate is mainly used as a cosmetic whitening additive. It is added to the oil phase when used, and the dosage is 1~3% of the total amount. In contrast, there are fewer descriptions of the usage and specific effects of kojic acid, but studies have shown that in clinical trials of kojic acid and kojic acid dipalmitate in patients with pigmentation, the efficacy of kojic acid and kojic acid dipalmitate is 60%-95% and 80%, respectively, indicating that kojic acid dipalmitate may be superior to the original kojic acid in whitening effect.

3. Effect: Kojic acid dipalmitate can not only improve skin pigmentation, fight against age spots, stretch marks, freckles and general pigmentation, but also has the effect of moisturizing the skin. These effects make kojic acid dipalmitate a popular cosmetic ingredient.

In summary, kojic acid dipalmitate is superior to the original kojic acid in cosmetics due to its stable chemical structure, high efficiency and safety, especially in whitening and anti-aging.