Phlorizin

Phlorizin

Product Name: Phloridzin

CAS: 60-81-1

EINECS: 200-487-1

Molecular Formula: C21H24O10

Molecular Weight: 472.45

Storage Conditions:Keep In Dark Place, Sealed In Dry, Room Temperature

Shipping: DHL.FedEx,TNT,EMS,SF

Shipping Speed:3-7 days

Payment: T/T,L/C,VISA......

Certificate: ISO9001,ISO22000,HALAL,KOSHER,FDA

Product Description

Phlorizin, also known as the glucoside of phlorizin, has the chemical name 1-(2-(beta-D-pyranose glucoseoxy)-46-dihydroxyphenyl)-3-(4-hydroxyphenyl)-acetone, and is a compound belonging to the dihydrochalcone class of flavonoids.

Phlorizin is mainly found in the root bark, stems, young leaves and apple fruits of apple trees, and also exists in small amounts in plants such as Asteraceae, Ericaceae, Leguminosae, Fagaceae, and Liliaceae. Phlorizin accounts for a relatively high proportion of the total content of phenolic substances in apple trees, and its content is so high that its existence can affect the overall existence of phenolic substances.

Phlorizin is a glycoside formed by the combination of phlorizin and glycosides as glucosides, and glucose is formed after the glycoside is hydrolyzed. It has many important biological activities such as lowering blood sugar, improving memory, and anti-allergic, and has potential utilization value in the food, beauty and health care products industries.

Product Details Form

Molecular Structure

Properties

1.Appearance: Phlorizin appears as slightly yellow needle-shaped crystals.

2.Solubility: At low content, phlorizin has good water solubility; but at high content, its water solubility is poor, but it is easily soluble in organic solvents such as ethanol.

Source Of Phlorizin

Phorizin is mainly found in plants of the genus Malus in the Rosaceae family. Phlorizin has also been reported in plants of the Asteraceae, Ericaceae, Leguminosae, Fagaceae, Liliaceae, etc., but the content is relatively low. Plants of the genus Malus are the main source of phlorizin and can be used as raw materials for extracting phlorizin. Apple branches, leaves, bark, etc. all contain a large amount of phlorizin. The distribution of phlorizin in apple fruits is concentrated in the seeds and peel.

 The Benefits Of Phloridzin

1.Anti-inflammatory and antioxidant

Phloridzin has certain antioxidant properties, which can induce and increase the activity of various antioxidant enzymes and prolong the lifespan of fruit flies. In addition, when phloridzin hydrolyzes and removes the glycoside group to generate phloridzin, its antioxidant capacity is stronger, which can remove free radicals in the body, reduce oxidative stress response, and protect cells.

Phloridzin also exhibits anti-inflammatory effects, can inhibit the production and release of inflammatory factors, and help relieve inflammatory responses.

2.Antibacterial

Phloridzin has an inhibitory effect on some bacteria and viruses and can be used as a potential antibacterial and antiviral drug.

The degradation product of phloridzin, phloridzinol, can effectively inhibit microbial activities, including the growth and reproduction of various plant pathogens, such as gray mold, fire blight, and scab fungus.

3.Hypoglycemic

Studies have shown that phloridzin has a good effect in the treatment of diabetes. Phloridzin is an inhibitor of sodium-glucose cotransporter (SGLT), especially SGLT1 and SGLT2. By inhibiting the activity of these transporters, phloridzin can reduce the reabsorption of glucose in the intestine and kidneys, thereby lowering blood sugar levels. For patients with diabetes, phlorizin can be used as a potential auxiliary therapeutic drug to help control blood sugar levels.

4.Improve memory ability

Studies have found that phlorizin can reduce the risk of cognitive impairment and improve memory ability by inhibiting blood sugar from entering the brain. This is related to its ability to cause transcription of the nuclei of neurons in the central nervous system and inhibit blood sugar from entering the brain.

5.Prevent osteoporosis

Phorizin can promote the proliferation and differentiation of bone cells, help maintain bone health, and prevent osteoporosis.

6.Protect cardiovascular and cerebrovascular health

Phorizin has the effect of protecting cardiovascular and cerebrovascular health. It can dilate blood vessels, increase blood flow, reduce blood viscosity, and prevent thrombosis. In addition, phlorizin can also lower cholesterol levels and prevent arteriosclerosis and cardiovascular and cerebrovascular diseases.

Application

Food

Phlorizin has a certain antioxidant capacity and can be added to food as a natural antioxidant to extend the shelf life of food. At the same time, since it also has the effect of reducing hyperglycemia, using it in Functional Foods can achieve the dual effects of reducing hyperglycemia and anti-oxidation at the same time.

Cosmetics

Phlorizin can reduce the formation of melanin by inhibiting tyrosinase, improve skin color, and whiten the skin. At the same time, it can prevent glucose from entering epidermal cells, slow down sebum secretion, and help prevent the occurrence of acne.

Medicine

Phlorizin can inhibit the reabsorption of glucose by the proximal tubules of the kidneys, increase urine sugar excretion, and thus reduce blood sugar levels. Clinical studies in recent years have shown that phlorizin has a good effect in the treatment of diabetes.

Phlorizin also has the effect of improving memory ability, providing a potential candidate substance for the development of new drugs.

Agriculture

Phlorizin has antibacterial properties and is closely related to the infection of plant pathogens. It may play an important role in the prevention and control of plant diseases.