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What is the introduction about palmitoylethanolamide?

2025-01-27

Palmitoylethanolamide is a white crystalline solid with high purity and stability. Due to its structural characteristics, palmitoylethanolamide has good solubility and biocompatibility.

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Palmitoylethanolamide, also known as palmitoylethanolamide or PEA (Palmitoylethanolamide), is an endogenous fatty acid amide. It is naturally produced in multiple systems and tissues of the human body, especially the central nervous system.

Palmitoylethanolamide is an endogenous fatty acid amide and belongs to nuclear factor agonists. It has the ability to bind to cell nuclear receptors and produce a variety of biological functions, especially those related to chronic pain and inflammation. The main target is considered to be peroxisome proliferator-activated receptor α (PPAR-α).

In addition, palmitoylethanolamide is not only an intermediate for pharmaceuticals and organic synthesis, but also can be used in laboratory research and development processes and chemical pharmaceutical research and development processes. It is also mentioned as an endogenous active compound that can be used to prevent respiratory viral infections. Due to its diverse biological properties and application potential, palmitoylethanolamide has received widespread attention in scientific research and medicine.

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Process flow of palmitoylethanolamide

Reaction→separation and purification process→filtration→redissolve in ethanol→hydrogenation→filtrate transparent liquid→crystallization→filtration→inspection→packaging-finished product

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Where does palmitoylethanolamide come from?

Palmitoylethanolamide is an endogenous substance naturally produced by the human body, mainly present in the central nervous system and other tissues. In addition, palmitoylethanolamide can also be prepared by chemical synthesis.

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What Are The Benefits Of Palmitoylethanolamide?

Anti-inflammatory

By changing gene expression to reduce the production of inflammatory signals, palmitoylethanolamide has been shown to have anti-inflammatory properties, can reduce inflammatory responses, and reduce the production of inflammatory mediators.

Analgesia

Studies have shown that palmitoylethanolamide can reduce pain sensitivity and has potential analgesic effects on chronic pain and neuropathic pain.

Neuroprotection

It can protect nerve cells and has a protective effect on the nervous system by inhibiting apoptosis and oxidative stress of nerve cells.

Pain Regulation

PEA can regulate pain perception and further reduce pain by affecting central cannabinoid receptor stimulation signals. 

Anticonvulsant properties

PEA also exhibits anticonvulsant properties and has a certain protective effect on the nervous system.

Other benefits: Palmitoylethanolamide also has biological effects such as regulating blood pressure, blood sugar and blood lipids.

 

What fields can palmitoylethanolamide be used in?

Food field

Although palmitoylethanolamide is relatively rarely used in the food field, it can also be used as a food additive to improve the texture and taste of food.

Cosmetic field

Palmamide ethanol has excellent moisturizing and emulsifying properties and can be used in cosmetics as an emulsifier, moisturizer and emollient.

Medical field

Due to its biological functions such as anti-inflammatory, analgesic and neuroprotective, palmitoyl ethanol has broad application prospects in the medical field. At present, studies have been conducted on its use in the preparation of drugs for the treatment of pain, inflammation, and nervous system diseases.