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98% Ifu ya Progesterone
Progesterone ni iki?
Progesterone ni endogenous steroid na hormone yimibonano mpuzabitsina ya progesterone hamwe na progesterone nyamukuru mumubiri, isohorwa nintanga ngore. Progesterone ni imisemburo ya karubone 21 ya karubone isohorwa na selile ovarian luteal selile. Nibicuruzwa biciriritse mugihe cyo guhuza imisemburo yose ya steroid kandi ni imwe muri progestine. Hariho uburyo bubiri bwa kristu, aribwo α-form na β-form. Imiterere ibiri ya kristu ifite ibikorwa bimwe bya physiologique. --Imiterere igwa muri dilute etanol kandi ni orthorhombic yera prismatic kristal. Form-form ni orthorhombic. Urushinge rwa kirisiti ya kirisiti yera, byombi bidashonga mumazi, bigashonga muri Ethanol, ether, chloroform, acetone, dioxane na acide sulfurike yibanze.
Ni izihe nyungu
01Uburinzi
Progesterone ifite uburinzi kandi ikumira ubudahangarwa bw'umubiri. Ubushakashatsi bumwe bwinjije uturemangingo tumwe na tumwe twibibyimba muri nyababyeyi. Gusa mu nyamaswa zatewe na progesterone, selile ntizigeze zangwa kandi zashyizwe mu rukuta rwa nyababyeyi, byerekana ko progesterone ishobora guhagarika ubudahangarwa bw'umubiri. Ibi birerekana kandi ko iyo umugore atwite bisanzwe, progesterone yiyongera, ibyo bikaba bishobora kubuza urusoro kwangwa na nyina kandi bigakomeza gutwita. Progesterone idahagije irashobora gutuma isoro ryangwa na nyina bikavamo gukuramo inda.
02Imbuto
Mugihe cya ovulation, mugikorwa cya progesterone isohorwa na corpus luteum, endometrium ihinduka kuva mugice cyinshi ikageza mugice cyibanga, bigatuma endometrium yakira insoro. Utugingo ngengabuzima twahinduwe tuvuye mu ngirabuzimafatizo ngengabuzima kandi turimo granules ya glycogene kugirango itange intungamubiri.
Progesterone irashobora gutuma habaho impinduka ya endometrium kandi ikagenga imvugo yibintu bitandukanye bifitanye isano no guterwa muburyo bwa autocrine cyangwa paracrine. Kubwibyo, progesterone irakenewe kugirango ikomeze reaction.
03 Kubuza kwikuramo nyababyeyi
Ubushakashatsi bumwe na bumwe bwemeza ko progesterone ishobora guhindura uburyo bwo kwanduza uturemangingo twa nyababyeyi tujya muri ion, igashyira ururenda mu buryo bukabije, bityo bikagabanya umunezero n’imikorere y’imitsi ya nyababyeyi, kandi bikagabanya ubukana bw’imitsi y’inda ibyara ibintu bitandukanye (harimo na oxytocine). Kumva neza, bityo bikabuza nyababyeyi kwirukana urusoro no kurinda uruhinja.
04 Abandi
Progesterone irashobora kongera insuline yo mu nda ikomeza kwiyongera k'isukari mu maraso y'ababyeyi, bityo bigatuma imikurire ikura. Progesterone irashobora kandi guteza imbere synthesis ya proteine zimwe na zimwe muri nyababyeyi, zifasha kubungabunga inda.
1.Mu gice cya kabiri cyukwezi kwimihango, itera gukura kwimitsi ya endometrale, ubwinshi bwa nyababyeyi, no kubyimba kwa endometrium kugirango witegure gutera amagi yatewe. Igabanya kandi umunezero wa nyababyeyi mugihe utwite, ikabuza ibikorwa byayo, kandi ikorohereza imitsi yoroshye. , kugirango urusoro rushobore gukura neza.
2. Mubikorwa bya estrogene, iteza imbere imikurire ya lobules na glande, kugirango amabere akure neza kandi yitegure konsa.
3. Funga inkondo y'umura, gabanya no kubyimba ururenda, kandi bigora intanga ngabo kwinjira; muri dosiye nini, irabuza gusohora kwa pitoito gonadotropine ikoresheje ibitekerezo bibi kuri hypothalamus, bityo ikabuza intanga ngabo.
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5. Kubuza kugabanuka kwa nyababyeyi no kugabanya ibyiyumvo bya nyababyeyi kuri oxytocine, bigatuma uruhinja rukura neza.
6. Kurwanya aldosterone, bityo uteze imbere gusohora Na na Cl na diuresis.
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Icyerekezo cyo gusaba
Progesterone ikoreshwa cyane mubijyanye na farumasi nubuvuzi
