Palmitoylethanolamide

PEA ni amide ikomoka ku ruhu rw’umubiri iri mu itsinda ry’abatera imbaraga za nuclear factor. Byagaragaye ko PEA ifatana n’uduce tw’umubiri turi mu gice cy’umubiri (receptors za nuclear) kandi ikagira imikorere myinshi itandukanye ya biyoloji ijyanye n’ububabare buhoraho n’ububyimbirwe. Intego nyamukuru ifatwa nk’agace k’umubiri gakoreshwa na peroxisome proliferator alpha (PPAR-alpha).

PEA ikora mu guhindura uburyo imiterere y’uturemangingo tumwe na tumwe ikoreshwa mu kugabanya ibimenyetso by’ubushyuhe, ndetse n’izindi nzira zishoboka zo kugabanya ububabare—ubushobozi bwo gukangura ibimenyetso binyuze mu buryo bwa cannabinoid mu mitsi.

Ubushakashatsi bwinshi bwakozwe mu buvuzi bwagaragaje ko PEA ifite ubushobozi bwo kurwanya ububyimbirwe, kurwanya nociceptive, kurinda ubwonko no kurwanya stroke; PEA ishobora kugenga imikorere myinshi y’umubiri, harimo no kumva ububabare, kuribwa mu nda, no kuvura ubwonko.