01
Ifu ya Vitamine K4
Vitamine K4 ni iki?
Vitamine K4 ni ifumbire mvaruganda hamwe nizina ryimiti 2-methyl-1,4-naphthodiol diacetate na formula ya chimique C15H14O4. Irakwiriye cyane cyane kubibazo bya coagulation biterwa no kubura vitamine K, nko kwinjiza amara. Kubura Vitamine K biterwa n'ingaruka mbi, jaundice itabangamira iterwa n'impamvu zitandukanye, kolite idakira ya kolite idakira, pancreatite idakira ndetse no kugabanya imikorere yo mu mara nyuma yo kwifata ruto ruto, gukoresha antibiyotike igihe kirekire bishobora gutuma vitamine K ibura umubiri, antibiyotike yagutse cyangwa imiti igabanya ubukana bwa bagiteri mu maraso asanzwe.
Ingaruka za farumasi
Nka coenzyme ya carboxylase, vitamine K4 igira uruhare muguhuza ibintu bya coagulation II, VII, IX, na X. Ibisigisigi bya aside glutamike kuri ibyo bintu bigomba gukora 9-12 γ- Acide Carboxyglutamic ituma ibyo bintu bigira ubushobozi bwo guhuza na Ca2 + no guhuza ibikorwa bya fosifolipide bityo bikabyara ibikorwa bya coagulation. Niba vitamine K4 ibuze cyangwa igabanuka rya epoxide irahagaritswe (nka antagonised na coumarine), synthesis yibintu II, VII, IX, na X bizaguma muburyo bwabanjirije, byongerera igihe prothrombine kandi bitera kuva amaraso.
Vitamine K4 ni umuti wa vitamine. Vitamine K4, izwi kandi nka prothrombine, ni ikintu gikora gitera umuvuduko w'amaraso hamwe na hemostasis, kandi ni kimwe mu bintu by'ibanze bikenerwa mu kugabana no gukwirakwiza. Kubura vitamine K4 bizagira ingaruka kumikurire isanzwe kandi bitera amaraso adasanzwe hamwe na episode nyuma ya hemorhagie. Hemostasis na coagulation biratinda.
Vitamine K4 irakwiriye kandi kuva amaraso ava mu mwana, impiswi ku bana bonsa cyangwa bagaburiwe ibihimbano, cyangwa kubura vitamine K biterwa n'izindi mpamvu. Rimwe na rimwe bikoreshwa kuri coli biliary iterwa na cholelithiasis cyangwa biliary ascariasis (biliary ascariasis). Nko gutabara abarozwe nuburozi bwa "sodium dimethonate" (hagomba gukoreshwa urugero rwinshi).
