Funda ngeSerrapeptase

I-Serrapeptase, ekwaziwa ngokuba yi-Serrapeptase okanye i-Serratopeptidase, yi-enzyme ye-proteolytic ephuma emathunjini ee-silkworms. Ekuqaleni yahlulwa kwi-Serratia marcescens E-15 kwaye yafunyanwa ngeminyaka yoo-1960. I-Serrapeptase ikhona ngokwemvelo emathunjini ee-silkworms kwindalo kwaye isetyenziswa kakhulu kwicandelo lezonyango.

I-Serrapeptase ineenzuzo ezininzi, njengokuba yiproteni yendalo ecocekileyo, ekhuselekileyo nengenabungozi enekhono elinamandla le-hydrolysis kunye noluhlu olubanzi lwezenzo. Kwiqondo elithile lobushushu kunye nexabiso le-pH, inokubola iiproteni ezinkulu zemolekyuli zibe ziimveliso ezifana nee-polypeptides kunye nee-amino acids, zenze incasa ye-hydrolysis eyahlukileyo.

I-Serrapeptase ikwanomsebenzi wokubola i-mucus kunye ne-pus, inokwenza i-pus kunye ne-sputum ibe manzi, ikhawulezise ukukhupha, kwaye ikhuthaze ukuvuselelwa kweeseli, nto leyo enokunceda ii-antibiotics zidluliselwe kwizilonda kwaye yonyuse isiphumo se-antibiotics sokulwa neentsholongwane.

Njengento esebenzayo ngokwebhayoloji, i-serrapeptase isengozini yokuthintelwa nokutshatyalaliswa kwee-ion zesinyithi esinzima (i-Fe3+, i-Cu2+, i-Hg+, i-Pb+, njl.njl.) kunye nee-oxidants, kwaye kufuneka ziphetshwe ngexesha lokugcinwa okanye ukusetyenziswa. Ukugcinwa ixesha elide kakhulu okanye kwiimeko ezingathandekiyo kuya kunciphisa umsebenzi we-enzyme ukuya kumaqondo ahlukeneyo. Ukuba ubushushu kunye nokufuma kuphezulu kakhulu, kuyimfuneko ukwandisa umthamo ngokufanelekileyo xa usetyenziswa.

Eyona nzuzo iphambili ye-serrapeptase ziimpawu zayo zokulwa nokuvuvukala, eziye zabonakala zinciphisa ukudumba kunye neentlungu ezinxulumene ne-arthritis kunye ne-carpal tunnel syndrome. Ukongeza, ingasetyenziselwa ukunciphisa iiplaque ezithintela ukuhamba kwegazi kwimithambo yegazi, ngaloo ndlela ithintele ukwenzeka kwestroke. I-Serrapeptase inokunciphisa kakhulu iintlungu kunye nokudumba emva kotyando lwamazinyo, kwaye isetyenziswa kakhulu eJapan ukunyanga izifo ezingapheliyo zomoya.

Yintoni umthombo kunye nenkqubo yokuvelisa i-serrapeptase?

Umthombo we-serrapeptase ikakhulu yi-silkworm, isilwanyana esincinci esikhethekileyo eTshayina. Abaphandi bafumanise ukuba emathunjini e-silkworm, kukho i-serrapeptase ekhethekileyo enokuthintela ngempumelelo ukudumba emzimbeni.

I-Serrapeptase yaqala yahlulwa emathunjini eembungu zesilika. Le enzyme ikhona ngokwemvelo emathunjini eembungu zesilika kwaye yahlulwa ngokwenziwa kwiembungu zesilika ngeminyaka yoo-1960. Inkqubo yokuvelisa i-serrapeptase ibandakanya i-microbial Serratia E-15 protease, eyayisetyenziswa ngaphambili ukunyanga amanxeba kunye nezinye iinjongo zonyango.

Zithini imisebenzi ye-serrapeptase?

1. Ukulwa nokuvuvukala

I-Serrapeptase inefuthe lokulwa nokuvuvukala, inokuthintela ukusabela kokuvuvukala, kwaye inciphise ukudumba kunye nentlungu ezinxulumene nokuvuvukala. Ingadlala indima yokulwa nokuvuvukala ngokuthintela umsebenzi we-fibrinolytic kunye nokuthintela ukwanda kokungena kwemithambo yegazi.

2. Ukuncipha kombala

I-Serrapeptase egqunywe ngaphakathi IthebhulethiIngasetyenziselwa ukunciphisa ukudumba okubangelwa kukwenzakala, utyando, izigulane ezine-sinusitis engapheliyo kunye nokungafumani ubisi kwabasetyhini. Oku kuthetha ukuba ayifanelekanga kuphela kubantu abadala, kodwa nakubantwana emva kotyando okanye ukwenzakala ukuze ibancede baphile ngokukhawuleza.

3. Khuthaza ukukhutshwa kwe-sputum kunye ne-pus

I-Serrapeptase inokubola ngokukhawuleza iiproteni eziguquliweyo, amahlwili e-bradykininogen kunye ne-cellulose, i-liquefy ne-thin pus, i-sputum, amahlwili egazi, njl.njl., yenze kube lula ukukhupha nokukhupha, ikhawulezise ukucocwa kwamanxeba, kwaye ikhuthaze ukuvuselelwa kwezicubu ze-granulation.

4. Ukuphucula amayeza okubulala iintsholongwane

I-Serrapeptase inokunceda ii-antibiotics ukuba zidlulele kwizilonda kwaye zonyuse impembelelo yee-antibiotics kwiintsholongwane. Oku kunokuphucula ukusebenza kwee-antibiotics kwizigulana ezinezifo ezosulelayo.

5. Khuthaza ukuphiliswa kwamathambo aphukileyo

I-Serrapeptase ikwanegalelo ekukhuthazeni ukuphiliswa kwamathambo kwaye ifanelekile kwizifo ezifana ne-gout, i-rheumatoid arthritis, i-osteoporosis, i-ankylosing spondylitis, njl.

Ingasetyenziswa phi i-serrapeptase?

1. Intsimi yokutya

I-Serrapeptase yiproteni engenabungozi engenazo iziphumo ebezingalindelekanga. Ingasetyenziselwa i-hydrolysis yeeproteni zezilwanyana nezityalo. Le enzyme ine-hydrolysis ephezulu kwaye inokuvelisa i-HAP kunye ne-HVP, ezizizithambiso eziphezulu kunye neziphuculi zesondlo sokutya. Ngokusebenzisa i-hydrolysis, i-serrapeptase inokubola iiproteni zibe ziimveliso ezifana nee-peptides kunye nee-amino acids, ngaloo ndlela iphucula ixabiso lesondlo kunye nencasa yokutya.

2. Icandelo lezonyango

I-Serrapeptase inokuthintela ukusabela kokudumba kwaye inciphise ukudumba okubangelwa lutyando, ukwenzakala, i-sinusitis engapheliyo, ukuqina kobisi, njl. Inganciphisa nokuqina kwe-sputum kunye ne-pus, okwenza i-sputum kunye ne-pus zinciphe kwaye kube lula ukuzikhupha.

3. Intsimi yeemveliso zempilo

I-Serrapeptase inokubola iiproteni ezinkulu zeemolekyuli zibe ziipeptides kunye nee-amino acids, nto leyo enceda ekuphuculeni izinga lokusetyenziswa kweeproteni. Kwiimveliso zokhathalelo lwempilo, ukusetyenziswa kwale enzyme kunokwenza iiproteni zibe lula ukufunxwa nokusetyenziswa ngumzimba womntu, ngaloo ndlela kuphucula ixabiso lesondlo leemveliso zokhathalelo lwempilo.

I-Serrapeptase inokunyibilikisa iiproteni zezilwanyana nezezityalo nge-hydrolyze kwaye iziguqule zibe ziipeptides ezincinci ze-molecular okanye ii-amino acids, ezithi zigaywe kwaye zifunxwe lula ngumzimba womntu. Ukongeza i-serrapeptase kwizongezo zempilo kunokunceda ukuphucula ukusebenza kwenkqubo yokugaya ukutya kunye nokukhuthaza ukufunxwa kwezondlo.

Yintoni endifanele ndiyiqwalasele xa ndithatha i-serrapeptase?

1. Ukutya

Ngexesha lokuthatha iipilisi ze-serrapeptase, kuyacetyiswa ukuba ungaseli. Utywala bunokuphazamisana nendlela esebenza ngayo i-serrapeptase, nto leyo enokubangela ukungasebenzi kakuhle okanye ukwanda kweempendulo ezimbi. Kwangaxeshanye, izigulana kufuneka ziqaphele ukutya okulula kwaye ziphephe ukutya okuneziqholo nokucaphukisayo.

2. Ukusetyenziswa kunye nomthamo

Umlinganiselo kufuneka uhlengahlengiswe ngokungqongqo ngokwesikhokelo soogqirha okanye iingcali.

3. Imiqathango yokusetyenziswa kwiindawo ezithile

Akucaci ukuba abafazi abakhulelweyo okanye abancancisayo banokusebenzisa iipilisi ze-serrapeptase, ngoko ke kuyimfuneko ukusebenzisa eli chiza ngononophelo ngokwengcebiso kagqirha. Abantu abanembali yokunganyamezelani na namayeza, iingxaki zokujiya kwegazi, kunye nobunzima obukhulu. ukungasebenzi kakuhle kwesibindi nezintso kufuneka uyisebenzise ngononophelo.

4. Ukusebenzisana kweziyobisi

Xa iipilisi ze-serrapeptase zisetyenziswa kunye ne-anticoagulants, isiphumo se-anticoagulant ngamanye amaxesha siyanda; xa zisetyenziswa kunye ne-antibiotics, amayeza e-chemotherapy, kunye ne-nonsteroidal anti-inflammatory drugs, zinokubangela iziphumo ezibi ezifana ne-skin mucosal eye syndrome kunye ne-toxic epidermal necrosis, i-interstitial pneumonia, kunye ne-eosinophilic pulmonary infiltration syndrome.